Signe Mosegaard and Riekelt Houtkooper, Laboratory Genetic Metabolic Diseases, Amsterdam UMC, received a Catalyst grant (€15.000) from United for Metabolic Diseases and Metakids, to develop prime-edited isogenic control lines and skeletal muscle cells derived from hiPSC with very long-chain acyl-CoA dehydrogenase deficiency (VLCADD).
Title project: ‘Induced Pluripotent Stem Cells (iPSC) derived muscle models to investigate pathophysiological mechanisms in very long-chain acyl-CoA dehydrogenase deficiency (VLCADD)’
The project is a collaboration with Pim Pijnappel, Erasmus MC, Sabine Fuchs, UMC Utrecht and Anke Tijsen, Department of Experimental Cardiology, Amsterdam UMC.
Read more about the project on the UMD website
Or have a look at the pitch (video number 4) about this project by Signe Mosegaard at the first UMD Catalyst grants webinar on September 22nd:
https://www.unitedformetabolicdiseases.nl/video.php
Riekelt Houtkooper
Signe Mosegaard
