Publications

 

1. Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T. et al. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.

2. Bellin, M., Marchetto, M.C., Gage, F.H.,  Mummery, C.L. Induced pluripotent stem cells: the new patient? Nat. Rev. Mol. Cell Biol. 13, 713–726 (2012).    

3. Antonetti, D. A., Klein, R. & Gardner, T. W. Diabetic retinopathy. N. Engl. J. Med. 366, 1227–1239 (2012).

4. Rask-Madsen, C. & King, G. L. Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors. Cell Metab. 17, 20–33 (2013).

5. Eremina, V. et al. VEGF inhibition and renal thrombotic microangiopathy. N. Engl. J. Med. 358, 1129–1136 (2008).

6. Gorelick, P.B.  et al., Vascular Contributions to Cognitive Impairment and Dementia: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association, Stroke 42, 2672–2713 (2011).

7. Söderman, M., Andersson, T., Karlsson, B., Wallace, M.C. Edner, G. Management of patients with brain arteriovenous malformations, Eur J Radiol 46, 195–205 (2003).

8. Hendriks, L. et al., Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene, Nat. Genet. 1, 218–221 (1992).

9. Kanekiyo, T., Xu, H., Bu, G. ApoE and Ab in Alzheimer’s Disease: Accidental Encounters or Partners? Neuron 81, 740–754 (2014).

10. Verghese, P.B., Castellano, J.M., Holtzman, D.M. Apolipoprotein E in Alzheimer's disease and other neurological disorders, The Lancet Neurology 10, 241–252 (2011).

11. Orlova, V.V., Drabsch, Y., Freund, C., Petrus Reurer, S., van den Hil, F.E., Muenthaisong, S., ten Dijke, P., Mummery, C.L. Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts, Arterioscler. Thromb. Vasc. Biol. 2014  34,177–186

12.Orlova, V.V., van den Hil, F.E., Petrus-Reurer, S., Drabsch, Y., ten Dijke, P., Mummery, C.L.. Endothelial Cells and Pericytes from human Pluripotent Stem Cells: methods for efficient generation, expansion and examination of functional competence. Nature Protocols 2014 in press.

13. Lebrin, F., Srun, S., Raymond, K., Martin, S., van den Brink, S., Freitas, C., Bréant, C., Mathivet, T., Larrivée, B., Thomas, J.L., Arthur, H.M., Westermann, C.J.J.,  Disch, F.,  Mager, J.J.,  Snijder, R.J., Eichmann, A., Mummery, C.L. Thalidomide stimulates vessel maturation and reduces epistaxis in Hereditary Hemorrhagic Telangiectasia patients. Nature Medicine (2010), 16(4):420-8.

14. Orlova, V.V. #, van der Meer, A.D. #, Dijke, ten, P., van den Berg, A., and Mummery, C.L. 2013. Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device. Lab Chip. 13:3562-3568. # Contributed equally to this work

15. Westein, E., van der Meer, A.D., Kuijpers, M.J., Frimat, J.P., van den Berg, A., Heemskerk, J.W. Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner. Proc Natl Acad Sci U S A. 2013 110(4):1357-1362.

16. Khairoun, M., de Koning, E.J., van den Berg, B.M., Lievers, E., de Boer, H.C., Schaapherder, A.F., Mallat, M.J., Rotmans, J.I., van der Boog, P.J., van Zonneveld, A.J., de Fijter, J.W., Rabelink, T.J., Reinders, M.E. Microvascular damage in type 1 diabetic patients is reversed in the first year after simultaneous pancreas-kidney transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2013;13:1272-1281.

17. de Vries, D.K., Khairoun, M., Lindeman, J.H., Bajema, I.M., de Heer, E., Roest, M., van Zonneveld, A.J., van Kooten, C., Rabelink, T.J., Schaapherder, A.F., Reinders, M.E.. Renal ischemia-reperfusion induces release of angiopoietin-2 from human grafts of living and deceased donors. Transplantation. 2013;96:282-289.

18. Khairoun, M., van der Pol, P., de Vries, D.K., Lievers, E., Schlagwein, N., de Boer, H.C., Bajema, I.M., Rotmans, J.I., van Zonneveld, A.J., Rabelink, T.J., van Kooten, C., Reinders, M.E.. Renal ischemia-reperfusion induces a dysbalance of angiopoietins, accompanied by proliferation of pericytes and fibrosis. American journal of physiology. Renal physiology. 2013;305:F901-910.

19. Bijkerk, R., van Solingen, C., de Boer, H.C., van der Pol, P., Khairoun, M., de Bruin, R.G., van Oeveren-Rietdijk, A.M., Lievers, E., Schlagwein, N., van Gijlswijk, D.J., Roeten, M.K., Neshati, Z., de Vries, A.A., Rodijk, M., Pike-Overzet, K., van den Berg, Y.W., van der Veer, E.P., Versteeg, H.H., Reinders, M.E., Staal, F.J., van Kooten, C., Rabelink, T.J., van Zonneveld, A.J. Hematopoietic microrna-126 protects against renal ischemia/reperfusion injury by promoting vascular integrity. Journal of the American Society of Nephrology : JASN. 2014;25:1710-1722.

20. van Solingen, C., Seghers, L., Bijkerk, R., Duijs, J.M., Roeten, M.K., van Oeveren-Rietdijk, A.M., Baelde, H.J., Monge, M., Vos, J.B., de Boer, H.C., Quax, P.H., Rabelink, T.J., van Zonneveld, A.J. Antagomir-mediated silencing of endothelial cell specific microrna-126 impairs ischemia-induced angiogenesis. Journal of cellular and molecular medicine. 2009;13:1577-1585

21. Junker, J.P., Noël, Guryev, V., Peterson, K.A., Shah, G., Huisken, J., McMahon, A.P., Berezikov, E.,  Bakkers, J. and van Oudenaarden, A. Genome-wide RNA tomography in the zebrafish embryo. Cell, in press (2014).

22. Grun, D., Kessert, L. and van Oudenaarden, A. Validation of noise models for single-cell transcriptomics. Nature Methods 11, 637 – 640 (2014).

23. Lekkerkerker, A.N., Aarbiou, J., van Es, T., Janssen, R.A.. Cellular players in lung fibrosis Curr Pharm Des. 2012. 18: 4093-102.

24. Michiels, F., van Es, H., van Rompaey, L., Merchiers, P., Francken, B., Pittois, K., van der Schueren, J., Brys, R., Vandersmissen, J., Beirinckx, F., Herman, S., Dokic, K., Klaassen, H., Narinx, E., Hagers, A., Laenen, W., Piest, I., Pavliska, H., Rombout, Y., Langemeijer, E., Ma, L., Schipper, C., Raeymaeker, M.D., Schweicher, S., Jans, M., van Beeck, K., Tsang, I.R., van de Stolpe, O., Tomme, P. Arrayed adenoviral expression libraries for functional screening. Nat Biotechnol 2002. 20: 1154-1157.