Core Publications

Fabricating porous, photo-crosslinked poly (trimethylene carbonate) membranes using temperature-induced phase separation. Thijs Pasman, Dirk W. Grijpma, Dimitrios F. Stamatialis and André A. Poot; Polimers Advances Technologies (2016) DOI: 10.1002/pat.3956​

Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells. Giacomelli E, Bellin M, Sala L, van Meer BJ, Tertoolen LG, Orlova VV, Mummery CL.Development. 2017 Mar 15;144(6):1008-1017. doi: 10.1242/dev.143438.

Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing Johan U. Lind, Travis A. Busbee, Alexander D. Valentine, Francesco S. Pasqualini, Hongyan Yuan, Moran Yadid, Sung-Jin Park, Arda Kotikian, Alexander P. Nesmith, Patrick H. Campbell, Joost J. Vlassak, Jennifer A. Lewis & Kevin K. Parker, Nature Materials (2016) Published online 24 October 2016 

Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come? Review. Sala L, Bellin M, Mummery CL. Br J Pharmacol. 2016 Sep 19. doi: 10.1111/bph.13577. [Epub ahead of print]  

Biology-Inspired Microphysiological System Approaches to Solve the Prediction Dilemma of Substance Testing (t4 Workshop Report) Marx U, Andersson TB, Bahinski A, Beilmann M, Beken S, Cassee FR, Cirit M, Daneshian M, Fitzpatrick S, Frey O, Gaertner C, Giese C, Griffith L, Hartung T, Heringa MB, Hoeng J, de Jong WH, Kojima H, Kuehnl, Leist M, Luch A, Maschmeyer I, Sakharov D, Sips AJAM, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tralau T, Tsyb S, van de Stolpe A, Vandebriel R, Vulto P, Wang J, Wiest J, Rodenburg M, Roth A; ALTEX 33(3), 2016, Epub May 15, 2016; doi:10.14573/altex.1603161

Cytostretch, an Organ-on-Chip Platform; Nikolas Gaio, Berend van Meer, William Quirós Solano, Lambert Bergers, Anja van de Stolpe, Christine Mummery, Pasqualina M. Sarro and Ronald Dekker, Micromachines 2016, 7(7), 120; doi:10.3390/mi7070120

Organs-on-chips in Drug Development: The importance of Involving Stakeholders in Early Health Technology Assessment; Heleen H.T. Middelkamp, Andries D. van der Meer, J. Marjan Hummel, Dimitrios F. Stamatialis, Christine L. Mummery, Robert Passier, and Maarten J. IJzerman, Applied In Vitro Toxicology, February 2016, DOI: 10.1089/aivt.2015.0029 

Microfluidic organ-on-chip technology for blood-brain barrier research; Marinke W van der Helm, Andries D van der Meer, Jan C T Eijkel, Albert van den Berg & Loes I Segerink, Tissue Barriers, Volume 4, Issue 1, 2016, Special Issue: Blood Brain Barrier DOI: 10.1080/21688370.2016.1142493Published online 28 January 2016

Reverse Engineering Human Pathophysiology with Organs-on-Chips; Donald E. Ingber, Cell, Volume 164, Issue 6, p1105–1109, 10 March 2016

The Promise and Potential of “Organs-on-Chips” as Preclinical ModelsBahinski Anthony, Applied In Vitro Toxicology. December 2015, 1(4): 235-242. doi:10.1089/aivt.2015.29002.rtl.

Workshop Meeting Report Organs-on-Chips: Human Disease Models. Anja van de Stolpe and  Jaap den Toonder, Lab on a chip 13, first published online 22 Mar 2013, 3449- 3470

Microfluidic Organs-on-Chips; Sangeeta N Bhatia & Donald E Ingber, Nature biotechnology 32,  Published online 05 August 2014, pages  760-772

International coordination of large-scale human induced pluripotent stem cell initiatives: Welcome Trust and ISSCR workshops white paper. Filipa A.C. Soares, Michael Sheldon, Mahendra Rao, Christine Mummery, and Ludovic Vallier, Stem Cell Reports 0, Published online 2014 Dec 9, pages 931-939

The Principles of Humane Experimental Technique. W.M.S. Russell and R.L. Burch, London: Methuen, New Edition 1992, especially pages 69-154

Innovative Human-Specific Investigational Approaches to Autoimmune Disease, Anja van de Stolpe and  Robert H. Kauffmann RSC Advances 5, First published online 04 Feb 2015, pages 18451 - 18463