Author Archives: hDMT

Double Dose consortium on cardiomyopathy

In February this year the Double Dose research program on cardiomyopathy kicked off. The program is financed by the Netherlands Heart Foundation and Stichting Hartedroom (€3.250.000 in total). The consortium is led by Jolanda van der Velden (Amsterdam UMC) and Rudolf de Boer (UMCG) and combines experts in preclinical research, clinical genetics, health technology assessment and clinical researchers with a strong clinical focus on cardiomyopathy in children and adults. The program will make use of extensive patient cohorts and the findings from DOSIS to optimize care for cardiomyopathy patients. The cost-effectiveness of current diagnostics and clinical care from both patient...

Read more

Pluripotente stamcellen bij hartziekten

Christine Mummery (hDMT partner LUMC and hDMT Executive Board Member) has contributed to the year book of Diligentia, De Koninklijke Maatschappij voor Natuurkunde. Some of the misunderstandings about what stem cells can and cannot do, and how they are generated in the lab are discussed. The article is in Dutch and can be downloaded via the following link here. “Een impressie van ‘jouw lichaam-op-een-chip”, credits to Berend van Meer, Mees de Graaf, and Claire Glashan. Summary of the lecture: The human heart is very different from that of a mouse. But the mouse is still the most used lab animal to...

Read more

Special issue Stem Cell Reports on Organs-on-Chip

The special issue of Stem Cell Reports on Organs-on-Chip is the first result of the collaboration between the International Society for Stem Cell Research (ISSCR) and the European Organ-on-Chip Society (EUROoCS). In the editorial the guest editors Christine Mummery and Peter Loskill, past chair and current chair of EUROoCS, welcome the readers of Stem Cell Reports to become inspired by the use of stem cell-derived tissues and organoids in Organ-on-Chip/microphysiological systems. The special issue includes commentaries on the future perspectives of Organ-on-Chip, interviews with pioneers in the field, and other interesting reports and articles with many contributions from hDMT researchers....

Read more

Tumor-LN-oC project has kicked off

On May 7th, 2021 the Tumor-LN-oC project (Tumor and Lymph Node on Chip for cancer studies) was officially kicked off. The project is coordinated by the Institute of Communication and Computer Systems from Greece. TU Eindhoven with the Microsystems group Jaap den Toonder is one of the 11 partners in the project. hDMT Managing Director Janny van den Eijnden-van Raaij and John Martens, coordinator of the hDMT Cancer-on-Chip group are members of the Advisory Board. The other partners involved in the Tumor-LN-oC project are the Biomedical Research Foundation Academy of Athens (Greece), Åbo Akademi (Finland), Alpes Lasers (Switzerland), Rayfos Ltd...

Read more

EUROoCS 2021 Awards for hDMT researchers of Delft and Leiden

EUROoCS (European Organ-on-Chip Society) Conference on 1st and 2nd of July (due to COVID-19 held online) prizes were awarded for the Best Presentation Award, Best Junior Presentation Award, Best Poster Award, Travel Award and Exhibition Quiz Award. Dutch hDMT researcher Ulgu Arslan from the Leiden University Medical Center won the Best Presentation Award and Milica Dostanić from Delft University of Technology won the Travel Award. The presentation awards were elected by a jury of 21 experts chaired by Erika Györvary (CSEM), Jose Tarazona (EFSA) and Maryam Shojaee (Uppsala University). Congratulations for both winners and all other awardees. Best Presentation Young Investigator...

Read more

hDMT INFRA on the national roadmap for large-scale research infrastructure

On 8 September 2021 Minister van Engelshoven has received the new National Roadmap for Large-Scale Research Infrastructures 2021. This Roadmap is intended as a guide for making strategic choices for investments in an innovative research infrastructure. In the new Roadmap, nine Groups (with substantive, thematic or technical overlap) present, on behalf of the Dutch research field, their proposals for investments in a large-scale research infrastructure for the coming ten years. This research infrastructure has the highest priority for science in the Netherlands and can qualify for NWO funding. In the coming five years, a total of 200 million euros will...

Read more

International MicroNanoConference 2021 Cancelled

Cancelled The MinacNed board has unfortunately had to decide to cancel the iMNC21 conference this year. More information here. ——— MinacNed organizes the 17th edition of the international MicroNanoConference. After a year and a half of mostly online webinars and meetings, we look forward to a live conference with you as our guest in Utrecht. The conference will take place on December 2 and 3, 2021 at the Jaarbeurs in Utrecht. A central location where science and industry will meet. The program for iMNC21 is focussed around the main theme: From science to market – scale-up in nanotech The program includes sessions...

Read more

Research theme challenges gut liver

A Gut-on-Chip and a Liver-on-Chip, or the combination of both model systems on an integrated platform requires a careful considerations of the minimal organ functionality that needs to be emulated in vitro. For several reasons innovative experimental models are needed, for instance to: understand the course of intestinal and liver diseases Better understand the natural course of both intestinal and liver diseases. For instance celiac disease, Crohn disease and other inflammatory bowel diseases. Inflammatory liver diseases that include fibrotic processes are still not fully understood, and clearly lack robust human like in vitro models, hindering our current understanding of the...

Read more

Sue Gibbs (Amsterdam UMC, ACTA)

Sue Gibbs is Professor of Skin and Mucosa Regenerative Medicine at the Department of Molecular Cell Biology and Immunology, Amsterdam UMC location VUMC and at the Department of Oral Cell Biology, ACTA. What sort of research are you doing? “My research is focused on human skin and oral mucosa biology, and in particular in animal alternative methods to develop novel therapeutic strategies for treating and preventing human disease. I combine research in stem cell biology and immunology with advances in tissue engineering. The current focus lies with developing next generation immune competent skin and mucosa tissue engineered constructs to understand the...

Read more

Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening

Vincent van Duinen, Wendy Stam, Eva Mulder, Farbod Famili, Arie Reijerkerk, Paul Vulto, Thomas Hankemeier and Anton Jan van Zonneveld (2020) Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening, Int. J. Mol. Sci., 21 (13), 4804.

Read more