Author Archives: hDMT

Sabeth Verpoorte and Pim de Haan authors of a guide on ‘organ-on-a-chip’.

An invited review co-authored by Prof. Sabeth Verpoorte and postdoc Pim de Haan (Pharmaceutical Analysis, University of Groningen) appeared in Nature Reviews Methods Primers on May 12, 2022. Entitled “Guide to the organ-on-a-chip”, this paper was written as a collaborative effort by an international team of organ-on-a-chip experts put together by Verpoorte. Pim de Haan is a shared first author of this work. Organs-on-chips are miniature versions of human tissues or organs that are interconnected with hair-fine microfluidic channels to supply them with growth medium and to take samples for analysis. They can be used to unravel and better understand...

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Young TPI launched

The Young Transition Animal-free Innovation (Young TPI) was officially launched last month and is now welcoming new members. Young TPI is a dynamic and engaging network composed of students, PhDs and young professionals focusing on the transition towards animal-free innovations (for example Organ-on-Chips and microphysiological systems). The network is connected and supported by the Dutch Ministry of Agriculture. The mission of Young TPI is to contribute to the acceleration of the transition to innovations without laboratory animals by providing open-minded input and raising awareness of animal-free options among young professionals, PhDs and students. Young people have the opportunity to work animal-free from...

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Practical models for flow research in the smallest blood vessels

On Tuesday, April 12th, 2022 Andreas Pollet successfully defended his PhD thesis entitled ‘In vitro models for investigating vascular flow: A toolbox for recreating the vasculature on chip’ at Eindhoven University of Technology (supervisors Jaap den Toonder and Massimo Mischi). Andreas explains the context and outcome of his research: ‘About one in two men and one in three women will develop cancer in their lifetime. Successfully combatting cancer requires imaging, treatment and monitoring of the tumour. Recently, a promising method has been introduced to visualise the smallest blood vessels in and around tumours. This is done by injecting small air...

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Next generation EUROoCS travel awards for students

The European Organ-on-Chip Society offers 10 travel grants to highly motivated students that are co-authors of accepted abstracts for the EUROoCS 2022 conference in Grenoble (France) on 4 and 5 July this year. The travel award, in the value of 150 euros, will support young researchers to participate in the conference. Application criteria are (i) to be graduate (BSc / first cycle completed, (ii) registered as a Master student and (iii) be a co-author of a submitted abstract. Applicants should send the following documents to EUROoCS-2022-nextGen@cea.fr mentioning ‘Next generation EUROoCS travel award’ as subject: Proof of graduate and student status from the...

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BNR Podcast: MEDICIJNEN SPECIFIEK GEMAAKT VOOR JOUW EIGEN LICHAAM

Medicijnen specifiek gemaakt voor jouw eigen lichaam: dat wordt mogelijk met de organ-on-chip technologie waar medici, techneuten en farmaceuten steeds vaker mee werken. Een orgaan op een chip? Hoe ziet dat er dan uit en wat kunnen we er allemaal mee? hDMT wetenschappers Berend van Meer en Bert de Vries, en Paul Vulto, CEO van Mimetas geven uitleg in deze podcast. In deze aflevering van BNR Eyeopeners bespreken we wat zo’n orgaan op een chip allemaal kan en waarom de farmaceutische en medische wereld er enthousiast over zijn. Is het een oplossing bij het bestrijden van ziektes als ALS, Crone en...

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3Rs student grants 2022: Call for submissions

The EPAA has published its call for the 2022 3Rs Student grants . The purpose of the grants is to sponsor students to participate in the major 3Rs events in 2020. One full grant (1000 EUR) and one half grant (500 EUR) will be awarded for each of the eligible events. You can find more information about the grants here: https://ec.europa.eu/growth/calls-expression-interest/3rs-student-grants-2022-call-submissions_en http://ec.europa.eu/growth/sectors/chemicals/epaa/

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3Rs Science Prize 2022: Call for submissions

The Call for submissions for EPAA’s 3Rs Science Prize 2022 has been launched. The €10,000 prize is granted every two years to a scientist with an outstanding contribution to 3Rs. EPAA wants to promote positive contributions from industry or academia and encourage more scientists to focus their research on the 3Rs goals. Scientists working on relevant methods for regulatory testing (e.g. safety, efficacy, batch testing) providing an outstanding contribution to the use of the 3Rs may apply for the prize. The call is available online on the EPAA website and can be accessed via the link: https://ec.europa.eu/growth/calls-expression-interest/3rs-science-prize-2022-call-submissions_en Applications should be sent to  grow-epaa@ec.europa.eu by Monday 3 October...

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EURL ECVAM Status Report 2021 on Alternative Methods published

The European Union Joint Research Centre for Alternatives to Animal Testing (EURL ECVAM) has issued its 2021 ‘Status Report on the Development, Validation and Regulatory Acceptance of Alternative Methods and Approaches’. The 2021 EURL ECVAM status report describes research, development and validation activities, as well as initiatives that promote the uptake and use of non-animal methods and approaches in science and regulation. The principle of the Three Rs, i.e. Replacement, Reduction and Refinement of animal use in basic, applied and translational research, as well as for regulatory purposes is firmly anchored in EU legislation, with full replacement of animal testing being the...

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EUROoCS Conference 2022 update

Information update for the upcoming annual EUROoCS Conference in Grenoble 4-5 July 2022. With more information about extended dealine submission, registration and information about the social event. The registration is open now, please use the following link. Deadline Early Bird Registration: 15 June 2022 Important note: Only EUROoCS members who paid their membership fee can benefit from discount for the EUROoCS 2022 conference. No EUROoCS member yet? Please first register as a new member. Abstract submission Deadline Extended: 30 April 2022 Your abstracts should be limited to a 1-page format according to the following template: EUROoCS 2022 Abstract Template Please upload your abstract via...

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BayesBrain, an Exploratory Multidisciplinary AI Research (EMDAIR) project, funded by the Eindhoven Artificial Intelligence Systems Institute

With our brains we perform parallel computer tasks, such as adapting and learning. Could it be that similar processes also take place in computers? Much research is already being done into new brain-inspired computation in the development of so-called neuromorphics chips. BayesBrain, led by TU/e researchers Regina Luttge and Bert de Vries, is trying a slightly different approach, because we still know far too little about how our brains actually work. ‘We therefore want to use existing computer architecture to control the brain and make it understandable. Of course, this cannot be done directly on a human brain. At the...

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