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Author Archives: hDMT
Portrait and video Luc van der Laan
Liver diseases have a significant impact on a patient’s life. Treatments don’t always succeed, and sometimes organ transplantation is the only way out. Luc van der Laan studies the most suitable treatment using organoids and seeks to better understand liver diseases. “A lot of trial and error is required, but ultimately, you make progress. It’s a matter of persistence.” Luc van der Laan is a professor of regenerative medicine and head of the Laboratory of Experimental Transplantation and Intestinal Surgery (LETIS) at Erasmus MC. He was recently appointed as a Medical Delta professor with an affiliation at TU Delft. Van der Laan...
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Vibrant NXTGEN Hightech Biomed Consortium meeting in Enschede
Last week, many partners within the #Biomed domain of NXTGEN Hightech reconvened in Enschede to update each other on the progress and highlights of the various projects within the domain.
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Deadline abstract submission EUROoCS 2024 extended: 12 February 2024
Still 1 month extra time to submit your abstract for the EUROoCS 2024 conference in Milan from 3-5 July 2024.
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SMART OoC annual consortium meeting
On 6 and 7 December 2023, the annual consortium meeting of the national collaborative project “SMART Organ-on-Chip” was held at the TU Eindhoven.
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Pre-announcement: developing future-proof high-tech equipment
NWO is expected to launch the call ‘Future-proof high-tech equipment’ in January 2024. This call is the first call stemming from the National Growth Fund programme NXTGEN Hightech. NWO provides funding for developing a new generation of high-tech equipment aimed at sustainability, digitalisation, health and technology sovereignty of the Netherlands. A total of 10.6 million euros is available for the public-private research. The call ‘Future-proof high-tech equipment – NXTGEN Hightech open call 2023′ focuses on research to promote the development of a new generation of high-tech equipment in the Netherlands. The Netherlands’ current strength in this field is due to...
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Sue Gibbs receives Willy van Heumen oeuvre award for non-animal scientific research
Sue Gibbs, professor of Regenerative Medicine at Amsterdam University Medical Center, received the Willy van Heumen oeuvre award on December 12th 2023 for her commitment to animal-free scientific research throughout her career. This award is presented every 10 years. Gibbs is nationally and internationally recognized as an innovator and advocate for non-animal scientific research. The Willy van Heumen Fund is named after a former resident of Heumen, Brabant, who wished to remain anonymous. The fund supports and stimulates research that brings animal-free science closer. It does so with a biennial prize as well as a ten-year oeuvre prize. This oeuvre...
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New hDMT theme group: Lung-on-Chip
The 10th hDMT theme group has been established and will kick-off soon: Lung-on-Chip.
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Review: The application of Organ-on-Chip models for the prediction of human pharmacokinetic profiles during drug development
Organ-on-chip (OoC) technology has led to in vitro models with many new possibilities compared to conventional in vitro and in vivo models. In this review, the potential of OoC models to improve the prediction of human oral bioavailability and intrinsic clearance is discussed, with a focus on the functionality of the models and the application in current drug development practice. Multi-OoC models demonstrating the application for pharmacokinetic (PK) studies are summarized and existing challenges are identified. Physiological parameters for a minimal viable platform of a multi-OoC model to study PK are provided, together with PK specific read-outs and recommendations for...
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Organ-on-Chip Centre Twente at TechMed event 2023
The Organ-on-Chip Centre Twente (OoCCT) was featured at the TechMed Event 2023, which took place at the University of Twente on November 1st 2023. The session entitled “Better designs, better health” was moderated by Liliana Moreira Teixeira, scientific lead of OoCCT, and attracted a diverse audience, including clinicians, researchers, and technology enthusiasts, all keen on exploring the latest advancements in healthcare technology. During the session, the OoCCT showcased its latest research and developments across three key areas, with local engineers collaborating closely with medical professionals. Topics covered included the Joint-on-Chip technology, Lung-on-Chip research, and the Heart-on-Chip company collaborations. The collaborative efforts with...
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