UMCG-hDMT kick-off mini-symposium on Organ-on-Chip
Organs-on-chip is an emerging technology allowing the modelling of parts of organs in micro-format, starting from induced pluripotent stem (iPS) cells. These platforms provide new ways to study human physiology & metabolism, perform drug discovery experiments, and model human disease. Excitingly, the field is moving into integrating multiple tissue chips in one closed microfluidic circuit, working towards a 'human-on-a-chip'.
Recently, the UMCG has become a member of the hDMT (human organ
and disease model technologies) consortium, which includes most
academic centres and multiple industrial partners in the
Netherlands. Membership in hDMT allows UMCG scientists to sign up
for and participate in general hDMT meetings on organ-on-chip
technology and specialist group meetings focusing on specific
organs-on-chip. Currently, researchers associated with the hDMT
consortium have organized themselves into focus groups around
several themes: cancer-, vessels-, heart-, skin-, brain-, and
intestine-on-chip. It is expected that other focus areas will be
established in the near future given
the rapid pace of the field.
Program
12:30 hDMT: Organs-on-chip consortium in the Netherlands, Janny
van Eijnden - van Raaij (hDMT)
13:00 Organs-on-a-Chip @ the RUG: A multi-interdisciplinary scene,
Sabeth Verpoorte (RUG)
13:30 Neurons-on-a-chip, an integrative platform in
neurodegeneration, Amalia Dolga (RUG)
13:50 NWO Zwaartekracht program NOCI: Towards Celiac
disease-ona-chip, Renée Moerkens (UMCG)
14:10 A 3D microfluidic chip model derived from patient iPS cells
to study Hereditary Hemorrhagic Telangiectasia, Valeria Orlova
(LUMC)
14:35 Tea Break; Pantry ERIBA 3rd floor
15:00 Genome engineering and stem cell services at the UMCG: what
can we offer? Floris Foijer (UMCG)
15:20 Blood perfusion of Organs-on-chip, Andries van der Meer
(UTwente)
15:45 Short Break
16:00 Keynote lecture and UMCG Molecular Medicine Seminar Emulating
human biology: Organs-on-Chips for disease modelling, drug
discovery, and personalized medicine, Katia Karalis (Emulate,
vice-president)
17:00 Closing