News

Sun, 10 September
A team led by hDMT scientist Christine Mummery (LUMC) has received a TKI-PPS grant of 180.000 Euro from Stichting Life Sciences Health for the development of a drug screening platform based on cardiomyocytes from hiPS cells of patients with the genetic heart disease CPVT. The research on the development of clinically relevant... Read more
Tue, 5 September
Luc Sala et al published a software tool that can be used to measure cell contractions. NB: This tool was also presented at the Interactive Masterclass with Kit Parker, 12 September 2017 in Amsterdam. Contraction of muscle reflects its physiological state. Methods to quantify contraction are often complex, expensive and tailored to... Read more
Tue, 5 September
The LUMC has granted the iPSC core facility extra finance to support the development of an "iPS cell Hotel". In a start up phase, 2 new postdocs and a technician will be trained to support training in the use of human induced pluripotent stem cells and the co-development of new differentiation protocols and gene modification... Read more
Tue, 5 September
Researchers from MERLN Institute for Technology-Inspired Regenerative Medicine hosted a symposium dedicated to the subject "Microfactories for Tissue Engineering or Regeneration on a Chip" at the European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society 2017 (TERMIS-EU 2017), in Davos,... Read more
Tue, 5 September
Dr. Paul Wieringa, researcher at the Department of Complex Tissue Engineering from MERLN / Maastricht University has been awarded with the prestigious Veni grant, from Netherlands Organisation for Scientific Research (NWO). This grant accounting for 250.000 euros, will allow this MERLN junior researcher to setup his innovative project... Read more
Wed, 23 August
LOCATE: Integrated platform to design novel cancer localization strategies by ultrasound microvasculature imaging A team led by hDMT scientist Jaap den Toonder (TU/e) has received a grant from NWO-TTW (total 1 Million Euro, 3 PhD students) to develop a novel experimental platform that enables to understand and develop ultrasound imaging... Read more
Wed, 23 August
PESCADoR: PhEnotypic Screening for CAncer DRug Discovery hDMT scientist Jaap den Toonder (TU/e) participates in a consortium that has obtained funding from the Academy of Finland (total 990 kEuro) to develop an experimental platform that recapitulates the architecture of human cancers for testing anti-cancer therapies as well as means... Read more
Fri, 18 August
Jean-Philippe Frimat (postdoc in the microsystem group at TU/eindhoven) has been awarded an Off Road grant (125.000 Euro) by ZonMW for his proposal on developing a Human brain biopsy on a chip. The purpose of the Off Road grants is to enable young biomedical researchers to achieve breakthroughs by doing out-of-the-box... Read more
Thu, 17 August
A team of PhD candidates Cinzia Silvestri, William Quiros Solano and Nikolas Gaio (start-up company Biond ) and Ronald Dekker (TU/e) have recieved an NWO Take-Off Grant (Phase 1) for organ-on-a-chip development. NWO Take-off focuses on facilitating and encouraging commercial and entrepreneurial activities initiated at... Read more
Thu, 17 August
An hDMT team led by researcher Dik van Gent (Erasmus MC) has received a grant from the Dutch Cancer Foundation (KWF) and financed by the Alpe d'HuZes funding scheme. The project team will develop a cancer-on-chip device that allows relatively long term culturing of (breast) tumor tissue. The project aims to develop and optimize... Read more
Wed, 16 August
hDMT is on the Science shortlist for the Lush Prize 2017. The prize is for individuals, research teams or institutions for work conducted on relevant toxicity pathways. Outstanding research producing an effective non-animal safety test based on an approach other than toxicity pathways, where none existed before, may also be considered. ... Read more
Wed, 16 August
Health~Holland, Top Sector Life Sciences & Health (LSH), launched the Knowledge and Innovation Agenda 2018-2021 titled Grow~Motion. This new strategic document describes the health and care ambitions for the next four years (2018-2021) in the Neterlands. hDMT is mentioned as one of the 18 mature (and thus operational) strategic... Read more
Tue, 15 August
6 minute video, in Dutch Read more
Tue, 11 July
DMD2017 is open for abstract submission. The venue of the conference this year is the High Tech Campus in Eindhoven the Netherlands. Topics include: Organ-on-Chip, Electroceuticals, Clinical Robotics, Smart catheter for cardiovascular interventions, Handheld diagnostics, Smart body patches, In-body / minimally invasive instrument... Read more
Mon, 3 July
Encouraged by the Dutch Enterprise Agency (RVO) representatives of the Mizuho Information & Research Institute in Tokyo visited hDMT at UTwente in Enschede on 18 January 2017. In commission of the Japanese NIH (AMED; Japanese Agency for Medical Research and Development), with involvement of the Japanese Ministry of Econcomy, Trade and... Read more
Mon, 3 July
Lenie van den Broek (VU University Medical Center, Amsterdam) received the Best Poster Award for the presentation of the poster on skin-on-chip during the International Organ-On-Chip Symposium 2017 at the EPFL Campus in Lausanne. Title poster: Skin-on-Chip: Integrating Skin-Tissue and Microsystems engineering. Authors:... Read more
Mon, 3 July
On 2 and 3 May, 2017 the 2nd hDMT International Organ-on-Chip Symposium took place at the EPFL campus in Lausanne. There were 120 participants from various countries and organizations, including universities, knowledge institutes and industry. Over 30 posters were presented and there... Read more
Fri, 9 June
hDMT researchers publish article in Science on safer drug testing using human cellular models hDMT researchers co-authored an article in Science on the effects of the chemical BIA1 10-2474 on human nerve cells. In 2016 in a clinical trial with this drug in Rennes, France, serious adverse events occurred affecting five participants, including... Read more
Mon, 8 May
hDMT researchers receive NWO Gravitation grant for 10 years of top level, curiosity-driven, scientific research The six NOCI PI's at the granting ceremony. From left to right: Hans Clevers, Christine Mummery (project leader), Lina Sarro, Jet Bussemaker (Minister of Health), Michel Ferrari, Albert van den Berg, and Sebo... Read more
Wed, 26 April
The American Food and Drug Administration (FDA) announced a multi-year research and development agreement with a company called Emulate Inc. to evaluate the company's "Organs-on-Chips" technology in laboratories at the agency's Center for Food Safety and Applied Nutrition, one of a number of FDA efforts to help... Read more
Mon, 24 April
The first VU Campus - hDMT meeting was organized at 21th of March to introduce hDMT research to the VU Campus and to present the several human organ and disease model technologies which are currently developed on the VU Campus. Speakers Sue Gibbs started with a presentation to introduce hDMT.In the second part of the program several VU... Read more
Fri, 31 March
Development published a special issue on organoids. Hans Clevers and Jarno Drost published an article in this issue: Translational applications of adult stem cell-derived organoids This special issue features original research articles on organoids representing a range of different organs, including the brain,... Read more
Fri, 24 February
At February 3rd the first annual hDMT Consortium Meeting was held. The meeting was hosted by the Hubrecht Institute in Utrecht.‚Äč At this "closed" meeting researchers from all hDMT partner organisations who are actively involved in hDMT research, from student to professor, could meet and mingle.... Read more
Thu, 23 February
See also the ERA-CVD newsletter january 2017 "Cardio-oncology: early detection and prevention of cardiac dysfunction and heart failure induced by cancer chemotherapeutics" received a grant from ERA-CVD Joint International Call (with ZonMW and Hartstichting)." Robert Passier (UTwente) is an hDMT... Read more
Thu, 23 February
ZonMw granted two projects by hDMT researchers. 1. Human stem cell-based high-throughput screening platform for cardiac disease Goal: In this research project we will use a human pluripotent stem-cell based heart on chip model where we measure important functional parameters of cardiomyocytes, such as contractility, electrophysiology... Read more
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