News

Mon, 27 July
CAAT and several other organizations are planning a "World Conference on Microphysiological Systems (MPS)" to be held in Baltimore/DC (USA) in the Fall 2021. Please share with them your input via https://www.surveymonkey.com/r/DW5M3KQ. Thank you for your help! Read more
Mon, 27 July
The NC3Rs is currently running a survey targeted to end-users of organ-on-a-chip technology. The aim of the survey is to gather information on the current use and application of the technology, provide insight into the impacts on the 3Rs and to help inform the NC3Rs' future strategy in this area. If you are currently using, considering... Read more
Wed, 8 July
hDMT chair Christine Mummery of Leiden University Medical Center becomes the new president of the ISSCR Board of Directors. Mummery's term of office leading the Society begins 1 July 2020. She will serve as ISSCR president for one year, succeeding Deepak Srivastava, Gladstone Institutes, USA. "I am thrilled to take on this... Read more
Wed, 1 July
On 25 and 26 August 2020 at 3 PM CET, the 11th World Congress on Alternatives and Animal Use in the Life Science will organize two 1.5 h webinars on 3Rs in COVID-19 research. On both days, several excellent presentations will highlight innovative model systems to study COVID-19, and will also discuss new strategies for the development of... Read more
Wed, 1 July
In U-Today, an independent journalistic medium at the University of Twente (UT), hDMT PI Andries van der Meer talks about plans to use Organ-on-Chips for covid-19 research, together with researchers from Leiden, among others. Their connections within the hDMT consortium inspired them to work together on this new challenge. Does the old... Read more
Tue, 30 June
Not only the lungs but in some cases also the heart of a patient can be seriously damaged by COVID-19. The cause of this is still unclear. By exposing heart tissue on an 'organ-on-chip' to both the virus and the medication used, fast and personalized evaluation of the causes is possible, including possible remedies. The TechMed... Read more
Tue, 30 June
hDMT PI Regina Luttge coordinates CONNECT, a Future and Emerging Technologies (FET) project, which aims at providing better treatment for neurodegenerative disorders, such as Parkinson's disease and Alzheimer's disease. In this regard, she was interviewed on the integration of the principles of microfluidics, tissue engineering and... Read more
Tue, 30 June
NanoNextNL has published an English version of the manifesto NanoVision 2030 containing an additional chapter on cooperation in research in the current corona era. Nanovision 2030 is a multi-year plan for the knowledge and innovation agenda around the key enabling technology, nanotechnology, for solving societal challenges. This aligns with... Read more
Sat, 13 June
The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN - the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies - will support research in the area... Read more
Wed, 10 June
Researchers from Leiden University Medical Center (group of hDMT PI Christine Mummery, Milena Bellin and Valeria Orlova) developed a microphysiological system that behaves as a "mini-heart" using cardiomyocytes, endothelial cells and cardiac fibroblasts all derived from human induced pluripotent stem cells (hiPSCs). These mini-hearts... Read more
Mon, 18 May
Researchers from the University of Twente (group of hDMT PI Severine Le Gac) and Radboudumc (group of Wouter Verdurmen) in Nijmegen, created an easy-to-fabricate microfluidic device that recapitulates essential features of the tumor environment including hypoxia and an acidic tumor microenvironment. In particular, the device mimics tumor... Read more
Fri, 15 May
hDMT PI Angelo Accardo of the Department of Precision and Microsystems Engineering (TU Delft) receives, together with Mohammad Mirzaali of the Department of Biomechanical Engineering (TU Delft), the 3mE Cohesion Grant of 200 k€ from Sectorplan funding. Current orthopaedic implants suffer from insufficient osseointegration rate in ageing... Read more
Fri, 15 May
Ahmed Sharaf recently joined the group of hDMT PI Angelo Accardo, Assistant Professor at Delft University of Technology, Department of Precision and Microsystems Engineering (PME). He is going to work on Light-assisted 3D manufacturing of neuronal microenvironments. The continuous evolution of additive manufacturing technologies opened a new... Read more
Wed, 13 May
Scientists in Leiden are looking for signals in blood samples to predict whether patients will develop serious COVID-19 symptoms or not. Based on that knowledge, they will be able to propose targeted therapies to prevent serious symptoms. They hope to come up with the first results within the week. Traces of diseases in the body ... Read more
Wed, 13 May
hDMT researcher Angelo Accardo, expert in the area of Soft Micro- and Nano-system Technology for Life Sciences and Biology, received the TU Delft Health Initiative Pilot award. The pilot project deals with the development of standardized, reproducible and physiologically relevant 3D engineered cell microenvironments (3D Onco-Scaffolds) to be... Read more
Fri, 8 May
Due to the global COVID-19 developments, the WC11 organization decided to postpone the 11th World Congress on Alternatives and Animal Use in the Life Science to August 22-26, 2021. The venue of the congress will remain the MECC Maastricht in the Netherlands. This decision also reflects public health concerns, and acknowledges the... Read more
Fri, 8 May
Due to the Covid-19 pandemic, the EUROoCS 2020 meeting will not be held in Uppsala on 8 and 9 July 2020 but will be replaced by a virtual meeting on the same days. The online meeting will be organized and supported by the University of Twente in the Netherlands. Don't miss the opportunity to listen to exciting talks, chat... Read more
Wed, 6 May
The International Society for Stem Cell Research has transformed its annual scientific meeting ISSCR on 23-27 June, into a virtual experience, bringing the global stem cell community together to share knowledge, collaborate, and network. Will you join? Join ISSCR and your colleagues for The Global Stem Cell Event - and take part in... Read more
Mon, 4 May
hDMT and the European Organ-on-Chip Society (EUROoCS) were represented during a three-day workshop in Berlin in June 2019, where 46 leading experts gathered to identify the challenges and hurdles as well as the solutions for the adoption of Microphysiological Systems (MPS), including Organ-on-Chip models. In an open discussion the... Read more
Sat, 2 May
Researchers from the Hubrecht Institute in Utrecht, Erasmus MC University Medical Center Rotterdam, and Maastricht University in the Netherlands using human intestinal organoids, have found that the coronavirus SARS-CoV-2, which causes COVID-19, can infect cells of the intestine and multiply there. These findings could explain the observation... Read more
Sat, 2 May
Britt van der Leeden recently joined the group of hDMT PI Sue Gibbs of the Amsterdam UMC, location VUMC. She is going to work on a Skin-on-Chip with flow, for research on neutrophil extracellular trap formation (NETosis) that drives burn-induced thrombosis and wound deepening. It is recently found that extensive microvascular thrombosis... Read more
Sat, 2 May
ZonMW has published on May 1, 2020, the subsidy call 'COVID-19 Bottom-up focus area 1&2'. This call focuses on two of the three focus areas of the COVID-19 programme, namely 1. predictive diagnostics and treatment and 2. care and prevention. Within this call, a separate budget has been allocated for animal-free innovations by... Read more
Sat, 2 May
Andrew Morrison recently joined the group of hDMT PI Sue Gibbs of the Amsterdam UMC, location VUMC. He is going to work on the Lymph node-on-Chip model project. This project is in collaboration with the Amsterdam Rheumatology Center for Autoimmune Diseases (ARCAID) in order to develop a functional 3D organotypic lymph node with integrated... Read more
Sat, 2 May
From October 2019 to January 2020, secondary school students could take part in a Pre-University Online Course from the Delft University of Technology, the Netherlands. One of the three modules dealt with Heart-on-Chip, researching living cells and tissues with the help of a chip: a new technology to learn more about the development of diseases... Read more
Thu, 30 April
Alireza Mashaghi and his colleagues from the Leiden Academic Centre for Drug Research have successfully developed an Organ-on-Chip model that imitates the most dangerous symptoms of Ebola. This new chip is used to test new drug candidates. The first results are promising and published in iScience. Currently, the World Health Organization and... Read more
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