News

Wed, 2 June
If you were not able to join the workshop Putting Science into Standards (PSIS) on standardization of Organ-on-Chip, please have a look at the presentations and discussions on the CEN-CENELEC website. On 28-29 April 2021 the Putting Science into Standards (PSIS) workshop on Organ-on-Chip was held online. This workshop was organized by... Read more
Wed, 2 June
hDMT contributed to an exploration by ZonMw for a Dutch research program for innovations without laboratory animals. The exploration was presented to minister Schouten (LNV) on 19 May 2021. On 19 May 2021 minister Carola Schouten of the Ministry of Agriculture, Nature and Food Quality received from Jeroen Geurts, chairman of ZonMw, an... Read more
Wed, 2 June
Congratulations to professor Christine Mummery from Leiden University Medical Center in the Netherlands who is co-recipient of the 2021 Scientific Grand Prize from the Lefoulon-Delalande Foundation of the Institut de France. The second laureate is professor Gordon Keller from the McEwen Stem Cell Institute and Princess Margaret Cancer... Read more
Sun, 2 May
Trillions of microorganisms live in human intestine and form a complex ecosystem. This ecosystem can undergo dynamic changes over time by showing a shift in its composition or genetic alternation on genomes of different species. By comparing the gut microbial composition and genetic makeup four year apart, this study showed several novel aspects... Read more
Sun, 2 May
Jingyuan Fu has been awarded a prestigious Vici grant from the Dutch Science Foundation (NWO) for her research project - Decoding the human genome and metagenome in cardiometabolic diseases. This award provides 1.5 M Euro to fund a 5-year research project. The funded project will explore how the gut bacterial genome is involved in... Read more
Wed, 21 April
As a result of the alliance with EUROoCS, Stem Cell Reports welcomes manuscripts on innovative studies incorporating stem cells or their derivatives into Organ-on-Chip and microphysiological systems. Topics include applications for functional genomics and disease modeling, and basic studies of cell interactions in tissue... Read more
Wed, 21 April
Per 1 January 2021 Utrecht University has joined hDMT as a new partner. The representatives in the hDMT Consortium Assembly are Bart Spee and Tina Vermonden. Utrecht University (UU) has an excellent research infrastructure in the area of human and animal measurement models, with strong expertise in pharmaceutical sciences, regenerative... Read more
Tue, 20 April
Researchers from Eindhoven University of Technology and Radboudumc have interwoven various bone cells into an 'organoid' that can independently make new, hard bone tissue. It's the most complete 3D model of bone formation to date. The 3D model allows for the study of the key biochemical processes in unprecedented detail and... Read more
Tue, 20 April
On April 9, the Cabinet announced that RegMed XB will receive a maximum of 56 million euros from the National Growth Fund for a regenerative medicine pilot plant. From the grant, 17 million euros will be allocated to the Netherlands Center for Clinical Advancement of Stem Cell & Gene Therapies (NecstGen) and the stem cell and organ-on-chip... Read more
Tue, 20 April
Under a cross-disciplinary program spearheaded by the Swiss Federal Institute of Technology in Lausanne (EPFL), scientists from MESA+, among others, will develop an AI-based system that can predict whether Covid-19 patients will develop severe cardiovascular complications. In the longer term these systems can detect the likely onset of... Read more
Tue, 20 April
In February, the postdoctoral scientist Franziska Linke joined the group of PI Dr. Wytske van Weerden within the Department of Urology at the Erasmus MC Rotterdam to work on the project "Building a multi-tissue microfluidics system of metastatic potential (BIOMEP)", as part of the programme Human Measurement Models 2019: towards... Read more
Tue, 20 April
From April 2021 Berend van Meer has been appointed as member of the hDMT Executive Board. Being microelectrical engineer by training (Delft University of Technology) and with a PhD in stem cell biology (Leiden University medical Center; LUMC), Berend feels comfortable both in the biological and technological domain - a useful combination... Read more
Tue, 20 April
Sekar Galuh is a new PhD student at LUMC since January 2021. Her research will mainly focus on implementing induced pluripotent stem cell studies in fundamental research on central serous chorioretinopathy. She will be supervised at LUMC by prof. C.J.F. Boon, prof. O.C. Meijer, and dr. E.H.C. van Dijk. The PhD trajectory of Sekar is a... Read more
Tue, 20 April
Due to the ongoing pandemics the hDMT theme group meetings are still being held online. Because of the high attendance many of the groups are considering alternating online and in-person meetings for the future. Following the Vessels-on-Chip and Cancer-on-Chip group all other groups now have a dual chairmanship. hDMT theme groups consist of... Read more
Tue, 20 April
hDMT has received funding (50k euro) from the program 'Small projects for routes of the Dutch Research Agenda 2020 (NWA)'. With this grant a detailed business plan will be developed for a long-term self-sustainable Organ-on-Chip (OoC) infrastructure in the Netherlands (hDMT INFRA). hDMT has received funding (50k euro) from the... Read more
Tue, 20 April
Dirk Lefeber (Radboudumc) receives a Vici grant worth 1.5 million euros. He will use this grant to investigate why sugar metabolism differs between organs by use of stem cell models of muscle and brain. This will provide him with essential information to develop high-precision sugar therapies to treat patients with severe illness due to... Read more
Mon, 19 April
The European Partnership for Alternative Approaches to Animal Testing (EPAA) supports students and young scientists with outstanding work in the field of alternative approaches to attend a high-profile scientific event. Every year, several high-profile international meetings bring together world-class scientists working on the development... Read more
Wed, 10 March
NWO has awarded the prestigious Perspectief grant to a multidisciplinary team of 10 researchers affiliated with hDMT. The € 4.8 million grant makes it possible to take the next much needed step in Organ-on-Chip (OoC) technology: a standardized docking plate with microfluidics and electronics where technical and tissue chips are clicked in... Read more
Wed, 3 March
PhD student Sofia Gomez joined the group of hDMT PI Dr Ye Wang and Prof Jaap den Toonder at Eindhoven University of Technology in January 2021, to work on the project named: Pneumatically actuated Heart-on-Chip platform with precise strain and frequency control for in vitro cardiac fibrosis modelling and beyond. In this project, she aims to... Read more
Tue, 2 March
The EUROoCS 2021 Annual Meeting will be organized on 1-2 July 2021, as an online event. Due to the pandemic, the EUROoCS 2021 conference will again be organized in digital format. Although this cannot replace the atmosphere and networking during a physical meeting in the sunny Uppsala, we are quite confident that EUROoCS 2021 will... Read more
Fri, 19 February
15 PhD students give you a virtual lab tour in 11 laboratories involved in the EUROoC International Training Network, where they are working on finding alternatives to reduce animal testing. You are guided through the processes of building and setting-up an Organ-on-Chip experiment for in vitro modeling and drug screening. 4 PhD students,... Read more
Fri, 19 February
The 2021 edition of the 'Putting Science into Standards' (PSIS) workshop will focus on Organ-on-Chip and is now open for registration. hDMT scientists are involved in the organization of the workshop as members of the Advisory Board. The 2021 PSIS edition will be focusing on Organ-on-Chip (OoC). This event aims to facilitate... Read more
Fri, 12 February
Human organoids hold tremendous potential for biomedical applications. These three-dimensional structures of cultured cells recapitulate important aspects of in vivo organ development and biological function. They provide tractable in vitro models of human physiology and pathology, thereby enabling interventional studies that are difficult or... Read more
Fri, 12 February
Recently a new release of the book Stem Cells: Scientific Facts and Fiction by Christine Mummery, Anja van de Stolpe, Bernard Roelen and Hans Clevers, has been published. The book has updated chapters with new illustrations on Organs-on-Chip and Organoid models for understanding disease mechanisms and testing drugs as well as a general... Read more
Wed, 10 February
In January 2021, George Galaris joined the Metabolic Health Research group at TNO, location Leiden, and the Division of Drug Discovery & Safety at Leiden Academic Centre for Drug Research (LACDR) as a post-doctoral researcher. Previously, Galaris performed his PhD studies at Leiden University Medical Centre (Nephrology... Read more
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