Dutch start-ups with Organ-on-Chip technology attract worldwide attention

Monday, 20 April

Dutch start-ups with Organ-on-Chip technology are attracting worldwide attention at the Start-up Grind Conference in Silicone Valley. That reflects the front page of the Dutch newspaper Trouw in the article 'A chip that beats like a heart and grows like a tumour.' Thanks to the cultivation of organ tissue on an advanced chip, every patient could get the perfect medicine in the future, is the perspective.

BI/OND, the spinoff from Delft University of Technology, develops hardware that biomedical scientists can use to mimic organs with living cells. The technology in the chip can make the heart cells beat and mimics a flow of blood that supplies the heart cells with nutrients. Their goal is to create personalized chips, which can be used to test drugs before they are administered. Another application is growing a patient's specific tumour tissue for testing chemotherapy, as hDMT researcher Dik van Gent at Erasmus MC in Rotterdam is doing to study the treatment of breast cancer in question.

"There are more interesting start-ups in the Netherlands, but also larger companies, such as Mimetas. Certainly in Europe, the Netherlands is leading the way in this field. We have the hDMT foundation, in which all universities work together to coordinate and improve each others research," explains hDMT PI professor Albert van den Berg of the MESA+ Institute of the University of Twente to Trouw. At his university, another initiative is recently launched: the Translational Organ-on-Chip-Platform (TOP) which develops a technology that links different organs together, for example, a heart and a lung, or a blood vessel and a kidney.

Source: Trouw, 9 Feb 2020. Een chip die klopt als een hart en groeit als een tumor. (in Dutch)

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