Interview with Regina Luttge about medical microsystems technologies
hDMT PI Regina Luttge coordinates CONNECT, a Future and Emerging Technologies (FET) project, which aims at providing better treatment for neurodegenerative disorders, such as Parkinson's disease and Alzheimer's disease. In this regard, she was interviewed on the integration of the principles of microfluidics, tissue engineering and electrophysiology into a Brain-on-Chip platform technology.
The primary aim is to make progress in modelling the mechanism of Parkinson's Disease. In this multidisciplinary domain of science, the implementation of an advanced human Parkinson's Disease model, based on the marriage of chip and stem cell technology is envisaged. This project is the first steppingstone for the long-term vision in truly finding effective personalized treatment modalities for people suffering from Parkinson's Disease and other shattering diseases being linked to the brain.
Her group Neuro-Nanoscale Engineering at Eindhoven University of Technology is going to build a system of entangled nano- and microliter volume-sized channels and containers that host, guide and support growth of axonal connections between the different types of cells in a systematic but in a vivo-like manner. Subsequently, the other project partners can use these systems for cell and tissue interactive studies to lift the understanding of Parkinson's Disease.
Read the full interview with Regina Luttge about medical microsystems technologies at the website of the European Commission.