Contribution of Mohammad Jouybar to new book on Organ-on-a-Chip
Mohammad Jouybar, researcher in Microsystems section at Technical University of Eindhoven (TU/e), has contributed to the 2nd chapter of a new book on Organ-on-Chip. This chapter introduces standard techniques and a novel method for including porous membranes within microfluidic devices. These porous membranes can be used to study tissue barriers within OoC applications.
The book Organ-on-a-Chip was recently published in Springer Nature Protocols, part of the Methods in Molecular Biology book series (MIMB, volume 2373). This book, which was edited by Marco Rasponi, is written in the format of the highly successful Methods in Molecular Biology series. Each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols for Organ-on-Chip (OoC) applications.
If you are searching for a collection of microphysiological systems employed by experts for chemical/drug screening and strategies to mimic various physiological conditions, please take a look at this book. Chapters guide readers through Organ-on-Chip platforms such as liver, intestine, blood-brain barrier, kidney, vessels, cardiac and skeletal muscles, articular joint, human fat. Additional chapters detail microfabrication technologies used to fabricate OoC devices such as, standard photo- and soft-lithography, techniques to fabricate membranes, and industrial-oriented fabrication methods.