FDA begins moving from animal testing to organs-on-chips
The American Food and Drug Administration (FDA) announced a multi-year research and development agreement with a company called Emulate Inc. to evaluate the company's "Organs-on-Chips" technology in laboratories at the agency's Center for Food Safety and Applied Nutrition, one of a number of FDA efforts to help evaluate this chip technology. The flexible polymer organ-chips contain tiny channels lined with living human cells and are capable of reproducing blood and air flow just as in the human body. The chips are translucent, giving researchers a window into the inner workings of the organ being studied.
Research will begin with a liver-chip but the agreement may expand in the future to cover additional organ-chips, including kidney, lung and intestine models. The ultimate goal is to predict how specific organs will respond to exposure to potential chemical hazards found in foods, cosmetics and/or dietary supplements with greater precision than other methods currently being used, such as cell-culture or animal-based tests.
Organs-on-Chips' Technology: FDA Testing Groundbreaking Science (April 11, 2017, US FOOD & DRUG ADMINISTRATION)
FDA Signs Collaborative Agreement with Emulate, Inc. to Use Organs-on-Chips Technology as a Toxicology Testing Platform for Understanding How Products Affect Human Health and Safety (April 11, 2017, Emulate)
The FDA Is Moving From Animal Testing To "Organs-On-Chips" (April 12, 2017, Futurism)