News

hDMT researchers publish article in Science on safer drug testing using human cellular models hDMT researchers co-authored an article in Science on the effects of the chemical BIA1 10-2474 on human nerve cells. In 2016 in a clinical trial with this drug in Rennes, France, serious adverse events occurred affecting five participants, including... Read more

hDMT researchers receive NWO Gravitation grant for 10 years of top level, curiosity-driven, scientific research The six NOCI PI's at the granting ceremony. From left to right: Hans Clevers, Christine Mummery (project leader), Lina Sarro, Jet Bussemaker (Minister of Health), Michel Ferrari, Albert van den Berg, and Sebo... Read more

The American Food and Drug Administration (FDA) announced a multi-year research and development agreement with a company called Emulate Inc. to evaluate the company's "Organs-on-Chips" technology in laboratories at the agency's Center for Food Safety and Applied Nutrition, one of a number of FDA efforts to help... Read more

The first VU Campus - hDMT meeting was organized at 21th of March to introduce hDMT research to the VU Campus and to present the several human organ and disease model technologies which are currently developed on the VU Campus. Speakers Sue Gibbs started with a presentation to introduce hDMT.In the second part of the program several VU... Read more

Development published a special issue on organoids. Hans Clevers and Jarno Drost published an article in this issue: Translational applications of adult stem cell-derived organoids This special issue features original research articles on organoids representing a range of different organs, including the brain,... Read more

At February 3rd the first annual hDMT Consortium Meeting was held. The meeting was hosted by the Hubrecht Institute in Utrecht.​ At this "closed" meeting researchers from all hDMT partner organisations who are actively involved in hDMT research, from student to professor, could meet and mingle.... Read more

See also the ERA-CVD newsletter january 2017 "Cardio-oncology: early detection and prevention of cardiac dysfunction and heart failure induced by cancer chemotherapeutics" received a grant from ERA-CVD Joint International Call (with ZonMW and Hartstichting)." Robert Passier (UTwente) is an hDMT... Read more

ZonMw granted two projects by hDMT researchers. 1. Human stem cell-based high-throughput screening platform for cardiac disease Goal: In this research project we will use a human pluripotent stem-cell based heart on chip model where we measure important functional parameters of cardiomyocytes, such as contractility, electrophysiology... Read more

The report on the 10th Annual Concertation and Consultation Workshop on Micro-Nano-Bio-Systems (MNBS 2016) has been published. It can be downloaded here This report covers the EU funded Research and Innovation MNBS cluster workshop held in Otranto, Italy, from 27th to 28th June 2016. The workshop was held within the... Read more

Facilitated by ENATRANS and EPTN, NanoNextNL, Dutch Cancer Society and NWO Domain TTW joined forces to organize a miniconference on nanomedicine and cancer on Nano World Cancer Day (February 2nd 2017). This conference in Oudaen Castle (Utrecht) was visited by a mix of scientists, engineers, policymakers and patient representatives. They... Read more

Connecting Researchers, Patients and Enabling Technologies Worldwide, personalized medicine is recognized as the next big dot on the horizon for health care. The program of the Health-RI conference, on December 1st, has given an insight into current and future developments of health research as well as initiatives to connect... Read more

The 27th of October the Erasmus MC hDMT awareness day was organized to introduce hDMT research to the Erasmus MC community and to identify and highlight organ-on-chip research lines within the Erasmus MC. Steven Kushner and Marjolein van Driel presented the brain and cancer on a chip research programs that are already active within the Erasmus... Read more

Ronald Dekker is explaining organ-on-chip and cytostretch. 13 & 14 December 2016 the International MicroNanoConference took place in the Beurs van Berlage in Amsterdam. We're looking back at a great event with impressive keynotes and inspiring presentations that can be downloaded here. ... Read more

The final workshop in the project hDMT/NanoInside: Organ-on-Chip Technology Platform took place at the TU Eindhoven on December 16, 2016. There were twenty participants, who used the workshop to inform each other about the results of the Pilot Projects that were carried out in the context of this hDMT/NanoNextNL-sponsored project. ... Read more

On 6 and 7 December 2016 a conference was organized by the European Union intended as a dialogue with the scientific community and relevant stakeholders, on how to exploit the advances in science towards the ultimate goal of phasing out animal testing. Christine Mummery held a presentation on the potential of stem cells. An extremely... Read more

A team led by hDMT Researcher Roland Kanaar (Erasmus MC) has received a grant from the Netherlands Organisation for Scientific Research (NWO) in the NWO programme Building Blocks of Life. The project team will visualize and quantitate the fundamental process of the DNA damage response (DDR) in tumors... Read more

A team led by hDMT Researcher Hans Bouwmeester (Wageningen University & Research) has received a grant from the Netherlands Organisation for Scientific Research (NWO) in the NWO programme Building Blocks of Life. The research will be performed at the chair groups of Toxicology and Microbiology of Wageningen University and the BIOS... Read more

On October 11th 2016 Berend van Meer (LUMC) presented a talk on Organ-on-Chips at TEDxYouth@ISH (De Hague International School). The event was organised for a select group of motivated highschool students (14- 17 years old). Van Meer: "The audience understood everything and I got very positive reactions. Most... Read more

Nikolas Gaio, Cinzia Silvestri and William Quiros Solano, 3 PhD's at Delft University of Technology, have filed a patent regarding their microfluidic device. Together with 4 other selected startups, their company BI/OND won the opportunity to participate in the Health Holland Life Sciences@Work venture challenge. The winner... Read more

On 8 september the MERLN Institute for Technology-Inspired Regenerative Medicine celebated its official opening. The institute belongs to Maastricht UMC+, one of the partners of hDMT. Read more

Janny van den Eijnden-van Raaij (managing director hDMT) represented hDMT and promoted Organ-on-Chip technology during the Stakeholders consultation on cross-cutting key enabling technologies in Brussels on 14 September 2016. Views of technology and service providers, system integrators, end-users and industry were presented and discussed.... Read more

lab visit at the TU Eindhoven The first workshop in the project 'hDMT/NanoInside: Organs-on-Chip Technology Platform' took place at the University of Twente on September 15. Over 40 researchers and representatives from hDMT partners and hi-tech companies participated in this one-day event that... Read more

Cytostretch, an Organ-on-Chip Platform by Nikolas Gaio et al. has been published in Micromachines' Special Issue Microfluidic Bioreactors and Organ-on-Chip Devices for Drug Screening and Disease Modeling. Micromachines is an open access journal on the technology and science of micro-scale machines and... Read more

The transatlantic think tank for toxicology (t4) has published the report Biology-Inspired Microphysiological System Approaches to Solve the Prediction Dilemma of Substance Testing. In the report, thirty-six experts from academia, industry and regulatory bodies present the results of an intensive workshop (held in June 2015,... Read more

Eurostars and the Netherlands Enterprise Agency (RVO) have announced a Promotional Call for Project Ideas to increase the Swiss - Dutch cooperation in innovation. A special focus is given to Microfluidics in life science applications. The Dutch funding for the 7th call in Eurostars is approximately 9.1 million... Read more