News

hDMT researcher Milena Bellin from the LUMC receives 2 million euros from the European Research Council (ERC). With this Consolidator grant, she will investigate human cardiac diseases using mini hearts made from stem cells. The aim is to improve this model so that it can be used to determine the cause of complex heart diseases. And ultimately... Read more

hDMT PI Jingyuan Fu of the UMCG Genetics/Paediatrics departments has received an ERC Consolidator Grant of 2 million euro from the European Union. She will use this the coming five years to investigate whether the effectiveness of medicines can be improved by making adjustments to the whole of micro-organisms in the gastrointestinal system... Read more

hDMT researchers from the UTwente recently published their article Modular operation of microfluidic chips for highly parallelized cell culture and liquid dosing via a fluidic circuit board in Microsystems & Nanoengineering which presents the development of a plug-and-play modular and standardized platform for research with Organ-on-Chip. ... Read more

In the second round of the Dutch Research Agenda Program: Research along routes by Consortia (NWA-ORC) the project Virtual Human Platform for Safety Assessment receives a grant of 9.9 million euros for assessing the safety of chemicals and pharmaceuticals without using laboratory animals. hDMT is closely involved in the project, as are hDMT... Read more

A 5 million Euro NWA-ORC grant was awarded to hDMT researchers to develop immunocompetent human Organ-on-Chip models with integrated lymph drainage for drug discovery and testing (LymphChip). The project is led by Valeria Orlova (coordinator) from Leiden University Medical Center (LUMC), Christine Mummery (LUMC) and Sue Gibbs (VUMC). ... Read more

The Lush Prize offers a global prize fund to support initiatives to end or replace animal testing. It is the largest prize fund in the non-animal testing sector. This year the winner of the Lush Prize for Training is the Helpathon Team from The Netherlands. Their innovative brainstorming sessions help scientists who currently use animals... Read more

After the successful launch of the Dutch version, as of today, also the English version of our booklet entitled 'Mini Organs-on-Chips: Towards new research models for studying disease and finding treatments', is available. It is also the first time that the Dutch Foundation 'Biowetenschappen en Maatschappij' offers... Read more

The Willy van Heumen Fund will award the Willy van Heumen Prize in 2021. The price is set at €15,000, to be spent at your own discretion on the welfare of animals. The Willy van Heumen Prize is a prize that is awarded once every two years by the Willy van Heumen Fund to a person or organization that has made a special contribution... Read more

Postdoc Viviana Meraviglia in the Dept of Anatomy and Embryology of LUMC has been awarded the 3Rs science prize 2020 of the European Partnership for Alternative Approaches to Animal Testing (EPAA) for her work using 3D mini hearts from human induced pluripotent stem cells. This was announced at the EPAA annual conference, on 10 November 2020. ... Read more

Win the Nano4Society Pitch Award (500 Eur cash) at iMNC2020 online? Then sign up today and give a great pitch in the main program on December 3. Extended abstract submission deadline: November 15, 2020 The iMNC2020 program is updated with excellent speakers who are ready to open discussions with you in the Nano4Society themes. hDMT... Read more

To highlight the new alliance with EUROoCS, Stem Cell Reports is seeking manuscripts on innovative studies incorporating stem cells or their derivatives into Organ-on-Chip and microphysiological systems for publication in an upcoming special issue of the journal. Topics include applications for functional genomics and disease modeling,... Read more

On Wednesday November 18th the Royal Dutch Chemical Association-KNCV organized a webinar on Organs-on-Chip: the new research weapon for disease and treatment. (in Dutch) If you missed the webinar, you can watch it back via Youtube. Organs-on-Chips are microfluidic chips containing human cells that mimic the function, dynamics and... Read more

A consortium of hDMT partner Leiden University Medical Center (LUMC) together with Bi/ond and Fluigent has received 1.4 million euros via the European Eurostars program for a new Organ-on-Chip system that mimics the physiological conditions of the human body. The two companies will deliver the very first compact Organ-on-Chip system that can... Read more

Your help is highly needed and appreciated in the next TPI-Helpathon #4 on November 2-3, 2020. The organizers are looking for people from all different disciplines - from basic research to regulatory till implementation. Helpathon #4 is called by three researchers at the Biomedical Primate Research Center, Rijswijk, the Netherlands.... Read more

Bi/ond, the Dutch startup of hDMT partner Delft University of Technology, has launched a new initiative to forward research on Organ-on-Chip research and develop better models. With this initiative, the startup aims to promote and accelerate the development of Organ-on-Chip models with the potential to reduce and replace animal testing. They... Read more

Today the Foundation 'Biowetenschappen en Maatschappij' has launched a booklet, entitled 'Mini Organs-on-Chips. Towards new research models for studying disease and finding treatments'. This new publication in the series of so-called 'Cahiers' explains to a large audience, in an easy-to-understand language,... Read more

Proefdiervrij together with Stichting Bouwstenen voor Dierenwelzijn recently awarded hDMT researcher Berend van Meer the Hugo van Poelgeestprijs 2020 for alternatives to animal testing for his work on human Heart-on-Chip models. "With his research into human heart models, Van Meer has shown that he has a vision of what the future may... Read more

As pre-event of the TechMed congress, the Organ-on-Chip Center Twente will be launched. The new center of expertise aimed to bring together researchers interested in Organ-on-Chip and share their knowledge. The Organ-on-Chip Center Twente (OoCCT) is supported by the MESA+ Institute and the TechMed Centre of the University of Twente. OoCCT... Read more

Post-Doc Jasper Koning and PhD Student Jonas Jäger recently joined the group of hDMT PI Sue Gibbs of the Amsterdam UMC, location VUMC. They are going to continue the NextSkin project which aims to develop a novel in vitro platform for testing penetration of actives via hair shafts in human metabolically and immune-competent skin... Read more

PhD Student Britt van der Leeden joined the group of hDMT PI Hans Niessen and Sue Gibbs of the Amsterdam UMC, location AMC and VUMC on 1st April. Her project is in collaboration with the Dutch burn wound association. In this project, she aims to unravel the mechanisms underlying burn-induced NETosis and resultant microvascular thrombosis and... Read more

PhD Student Melis Asal recently joined the group of hDMT PI Sue Gibbs of the Amsterdam UMC, location VUMC. She is going to develop an immune competent organotypic Gut-on-Chipmodel capable of immune surveillance. The model will be used for mimicking the effect of microbiome, testing immune responses and uptake of orally digested drugs for... Read more

hDMT researcher Liliana Moreira Teixeira Leijten of the University of Twente has received an ENW-KLEIN grant for her research into gendered chips for healthy knees and hips. The grant is awarded by the science financier NWO and consists of about 300.000 euros. Gendered chips for healthy knees and hips A multitude of approved drugs and... Read more

hDMT PIs Jessica de Greef from LUMC in Leiden, Pim Pijnappel from Erasmus MC and Coen Ottenheijm from Amsterdam UMC, received a grant from Health Holland/Prinses Beatrix Spierfonds to further develop their 3D Muscle-on-Chip model for research on muscle diseases. The Dutch television program '5 Hours Show' paid attention to their... Read more

On July 1st, 2020 Bjorn de Wagenaar joined the Electronic Components, Technology and Materials (ECTM) group of the Department of Microelectronics of Delft University of Technology, as a postdoc on the Moore4Medical program under the supervision of Massimo Mastrangeli. "After finishing my master in Biomedical Engineering on the... Read more

In August 2020, Nele Revyn joined the ECTM group at TU Delft as a PhD student under the supervision of Prof. Lina Sarro and Dr. Massimo Mastrangeli. Her background lies in digital and analog chip design, and her work will feature within the Netherlands Organ-on-Chip Initiative (NOCI). Revyn's research will encompass the Brain-on-Chip... Read more