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Scientists in Leiden are looking for signals in blood samples to
predict whether patients will develop serious COVID-19 symptoms or
not. Based on that knowledge, they will be able to propose targeted
therapies to prevent serious symptoms. They hope to come up with
the first results within the week.
Traces of diseases in the body
...
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hDMT researcher Angelo Accardo, expert in the area of
Soft Micro- and Nano-system Technology for Life Sciences and
Biology, received the TU Delft Health Initiative Pilot award. The
pilot project deals with the development of standardized,
reproducible and physiologically relevant 3D engineered cell
microenvironments (3D Onco-Scaffolds) to be...
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Due to the global
COVID-19 developments, the WC11 organization decided to postpone
the 11th World Congress on Alternatives and Animal Use in the Life
Science to August 22-26, 2021. The venue of the
congress will remain the MECC Maastricht in the Netherlands.
This decision also reflects public health concerns, and
acknowledges the...
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Due to the Covid-19
pandemic, the EUROoCS 2020 meeting will not be held in Uppsala on 8
and 9 July 2020 but will be replaced by a virtual meeting on the
same days. The online meeting will be organized and supported by
the University of Twente in the Netherlands.
Don't miss the opportunity to listen to exciting talks,
chat...
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The International Society for Stem Cell Research has transformed
its annual scientific meeting ISSCR on 23-27 June, into a virtual
experience, bringing the global stem cell community together to
share knowledge, collaborate, and network.
Will you join?
Join ISSCR and your colleagues for The Global Stem Cell Event -
and take part in...
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hDMT and the European
Organ-on-Chip Society (EUROoCS) were represented during a three-day
workshop in Berlin in June 2019, where 46 leading experts gathered
to identify the challenges and hurdles as well as the solutions for
the adoption of Microphysiological Systems (MPS), including
Organ-on-Chip models.
In an open discussion the...
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Researchers from the Hubrecht Institute in Utrecht, Erasmus MC
University Medical Center Rotterdam, and Maastricht University in
the Netherlands using human intestinal organoids, have found that
the coronavirus SARS-CoV-2, which causes COVID-19, can infect cells
of the intestine and multiply there.
These findings could explain the observation...
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Britt van der Leeden
recently joined the group of hDMT PI Sue Gibbs of the Amsterdam
UMC, location VUMC. She is going to work on a Skin-on-Chip with
flow, for research on neutrophil extracellular trap formation
(NETosis) that drives burn-induced thrombosis and wound
deepening.
It is recently found that extensive microvascular
thrombosis...
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ZonMW has published on
May 1, 2020, the subsidy call 'COVID-19 Bottom-up focus
area 1&2'. This call focuses on two of the three focus
areas of the COVID-19 programme, namely 1. predictive diagnostics
and treatment and 2. care and prevention.
Within this call, a separate budget has been allocated for
animal-free innovations by...
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Andrew Morrison recently joined the group of hDMT PI
Sue Gibbs of the Amsterdam UMC, location VUMC. He is going to work
on the Lymph node-on-Chip model project.
This project is in collaboration with the Amsterdam Rheumatology
Center for Autoimmune Diseases (ARCAID) in order to develop a functional 3D
organotypic lymph node with integrated...
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From October 2019 to January 2020, secondary school
students could take part in a Pre-University Online Course from the
Delft University of Technology, the Netherlands. One of the three
modules dealt with Heart-on-Chip, researching living cells and
tissues with the help of a chip: a new technology to learn more
about the development of diseases...
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Alireza Mashaghi and his colleagues from
the Leiden Academic Centre for Drug Research have successfully
developed an Organ-on-Chip model that imitates the most dangerous
symptoms of Ebola. This new chip is used to test new drug
candidates. The first results are promising and published in
iScience.
Currently, the World Health Organization and...
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The Neuro-Nanoscale Engineering research
group of Microsystems section of hDMT PI Regina Luttge at the
Eindhoven University of Technology sheds light on how microsystems
technology can benefit 3D Nervous-systems-on-Chip models.
The Neuro-Nanoscale Engineering group welcomes Dr. Yagmur
Demircan Yalcin as a postdoc fellow. She is working...
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The second edition of the conference 'Life-on-Chip - Enabling
personalized medicine by cross-over innovation' attracted almost
200 participants. A resounding success, according to the organizing
parties. This year's conference was dominated by innovations in
life sciences and crossovers with other technologies such as micro-
and...
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Cancer mutations in the colon can be caused by common gut
bacteria that produce the carcinogen colibactin. This was
demonstrated by researchers from Hubrecht Institute (KNAW) and
Princess Máxima Center in Utrecht in the Netherlands. The
results of this research were published in Nature.
By exposing cultured human mini-guts (organoids)...
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The European Partnership for Alternative Approaches to Animal
Testing (EPAA) is proud to announce that a call for submissions is
now open for its 2020 3Rs Science Prize.
Application deadline: 5 October 2020 at 12:00 (noon)
Brussels time
The EPAA aims to
promote the development, validation and acceptance of 3Rs
alternative approaches...
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In nearly two years the EU-funded ORCHID project built
a roadmap for Organ-on-Chip (OoC) technology and established a
European network in this promising field.
"ORCHID clearly identified strengths of the field in Europe, but
also the needs, challenges and barriers of the technology towards a
European roadmap," states project...
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BI/OND challenges every
Organ-on-Chip company such as River BioMedics, Darwin Microfluidics
and BEOnChip (Biomimetic Environment On-Chip) to contribute by
donating to research groups.
"Today we are donating a set of chips for a Lung-on-Chip model
to the Swiss Federal Institute of Technology (EFPL) in Lausanne and
researcher Vivek...
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Dutch start-ups with
Organ-on-Chip technology are attracting worldwide attention at the
Start-up Grind Conference in Silicone Valley. That reflects the
front page of the Dutch newspaper Trouw in the article 'A chip that
beats like a heart and grows like a tumour.' Thanks to the
cultivation of organ tissue on an advanced chip, every...
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Jorik Amesz, a
biomedical engineering master student from Delft University of
Technology, came just before the lockdown back from Spain after an
internship of six months.
Last year, he followed the lecture of professor Ronald Dekker
about Organ-on-Chips and became enthusiastic about the research
field. Via Dekkers contacts and the hDMT...
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In February, het
Financieele Dagblad, a Dutch newspaper which focuses on business
and financial matters, highlighted the high promise of
Organ-on-Chip technology for drug development in a big story
entitled "A complete Body-on-Chip". Besides Mimetas and Galapagos,
hDMT managing director Janny van den Eijnden-van Raaij and hDMT
PI...
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The fourth annual hDMT
Consortium Meeting took place on Friday February 14, 2020, again at
the English Meeting Center in Rotterdam. The
meeting illustrated the enthusiastic interdisciplinary interactions
that characterize hDMT. Junior and senior researchers mingled in an
open and cordial atmosphere.
The hDMT Consortium Meetings have become an...
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This annually recurring open Call, organized by Holland High
Tech, links high tech research innovations in public-private
partnerships to social themes. Scientists can win an amount of
€ 25,000 for a research project performed in collaboration
with at least one entrepreneur.
The Call for Proposals 2020 is...
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Associate Professor of
Pharmacology Antoinette Maassen van den Brink from the Erasmus
Medical Center in Rotterdam, will receive 1.5 million euros from
the Netherlands Organisation for Scientific Research (NWO) for
research on migraine and risk on cardiovascular disease.
This Vici grant will enable her to expand her research and team
over the...
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On Wednesday 1 April
2020, hDMT chair Christine Mummery, professor of Developmental
Biology at Leiden University Medical Centre, explained on Dutch
television why we still need animal testing. You can see the
broadcast here (in Dutch, 11 min)
If you want to learn more, Mummery answers four more questions of viewers after the
broadcast...
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